Dr. Hudson Freeze

Getting a cure is pretty difficult, but it starts from doing research. It starts from understanding the basic processes, the scientific processes, the physiological processes.

Dr. Hudson Freeze is Professor and Director of the Genetic Disease Program in the Sanford Children’s Health Research Center at Sanford-Burnham Medical Research Institute.

Sanford-Burnham Medical Research Institute is dedicated to discovering the fundamental molecular causes of disease and devising the innovative therapies of tomorrow. Sanford-Burnham takes a unique, collaborative approach to medical research and has established major research programs in cancer, neurodegeneration, diabetes, and infectious, inflammatory, and childhood diseases. The Institute is especially known for its world-class capabilities in stem cell research and drug discovery technologies.

Dr. Freeze graduated from Indiana University in 1968, where he studied bacteria in the hot springs of Yellowstone National Park. He came to San Diego to attend graduate school at UC San Diego and did nearly all of his postdoctoral training there, too, except for a brief detour into the acting field. Dr. Freeze was on the faculty at UC San Diego for several years, and then was recruited to the faculty at Sanford-Burnham Medical Research Institute in 1988, when it was known as the La Jolla Cancer Research Foundation. He’s currently the director of the Institute’s Genetic Disease Program, as well as President for the Society for Glycobiology.

Dr. Freeze’s work focuses on the inherited diseases that result from faulty glycosylation, the process by which cells add sugar chains to proteins and lipids in cells. Sugar molecules are required for the proper function of almost every cell in the body—an often overlooked fact of biology. He is driven by the search for novel therapeutics to treat patients with inherited genetic mutations leading to glycosylation defects called Congenital Disorders of Glycosylation or CDGs.

Podcast:

April 18, 2012

01: Lottery Jackpots and the Stock Markets

Learn how to recognize dangerous behavior that is hard-wired into our prehistoric brains and how you can outsmart your instincts and protect your fortunes.

02: Today's Odds of Winning in the Stock Market

What motivates people to make investments even when the odds are totally against them? Brian shares 114 years of stock market history and how investors tend to ignore easy to identify patterns. Brian welcome's Dr. Hudson Freeze, Director of The Genetic Disease Program at the Sanford Children's Health Research Center.

03: What Would You Do If You Were Told that Your Child had a Rare Disease?

Brian talks with Dr. Hudson Freeze, Director of the Genetic Disease Program at the Sanford Children’s Health Research Center in La Jolla to discuss cutting edge research that is being done to discover treatments and cures for children with rare genetic disorders.

04: Genetic Mapping is Making the Impossible, Possible

Dr. Freeze and his team at Sanford-Burnham Medical Research Center use cutting edge genetic technology to help children who have diseases that most doctors and scientists have never even heard of!